Recently there have been multiple articles here at PlasticsToday that I have enjoyed concerning Scientific Molding and the concept of 'Pushback' or resistance to it. Both articles had some good points and being one of the consultants called into question, if I may, my two cents...
The term Scientific Molding, as both have articles stated, describes a methodology, process, or steps one takes in optimizing a molding process for a particular mold. If done correctly and consistently, the results are more profits for the bottom line, accepting that the job was quoted properly to begin with.
Downsides to scientific molding: none. Though pride and other issues may arise since it's all based on numbers and data generated on the machine, running a particular mold. An example is a case of gate blush on a cosmetic part.