Medical Musings: Focus tightens on scaffold plastics


One of the Holy Grails of tissue engineering is development of a safe bioasorbable material that can be engineered to meet specific implant demands.

Several polymers are bioabsorbable, but lack the ability to be compressed for device delivery and then resiliently expand at the intended biological site. Or they lack sufficient porosity to promote adequate cellular ingrowth and proliferation.

These polymers include aliphatic polyesters and homopolymers and copolymers (random, block, segmented and graft) of monomers such as glycolic acid, glycolide, lactic acid, and, trimethylene carbonate. Polylactic acid is one of the most commonly used bioabsorbable plastics for human implant applications, such as bone anchors.
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