16/07/2010

www.tpe-magazine.com

Lubricious coatings improve performance of medical devices

Lubricious coatings have found widespread use on a variety of medical devices where clinicians need to reduce the amount of friction encountered between the device and a patient's tissue. For instance, they give surgeons better handling and maneuverability when performing procedures like cardiovascular stenting.
Baymedix CL 100 can be adapted to many substrates but is especially suitable for application to elastomeric materials common in catheters, such as polyetherblock amide (Pebax), TPU TPU, and nylon.
Impressively low coefficients of wet friction, 0.02-0.03, have been achieved on several prototype devices. Distinct from other lubricious and hydrophilic coatings, Baymedix CL 100 is directly grafted onto the surface of the medical device rather than applied as a separate coating. As a result, the coating is covalently attached to the substrate, giving superb adhesion and durability. This also means an especially thin coating of no more than a few microns.
The activation and surface modification processes take place in aqueous conditions, without solvents that can complicate manufacture. The process is scalable and suitable for various medical devices, since the raw materials are affordable and no special equipment is needed to cure the coatings.
Especially unique is, according to BMS, the ability for the product to be applied to the lumens, or inside surface, of catheters. Lumen coatings are useful where one catheter or device needs to be passed through another. "Because the coating is grown directly from the device surface, there's really no limit to the shape of part we can treat,” explains Dr. Paul Nowatzki, medical business development manager, Bayer MaterialScience LLC.
Bayer said in a statement that is committed to building a medical coatings business and is actively seeking customer feedback on this new product concept. Bayer is able to coat customer samples in its facilities and return the coated parts for evaluation. In addition, Bayer is well prepared to provide manufacturing and regulatory support to help ensure the success of customers' medical devices.

www.tpe-magazine.com