An in vitro diagnostic (IVD) biosensing platform that integrates cellulose paper and flexible polyester film could be used remotely to detect and determine treatment for a range of bacterial conditions without the need for expensive infrastructure or skilled personnel. The device can be used to identify HIV, E. coli, Staphylococcus aureas and other bacteria from a single drop of blood. A compatible app that detects bacteria and disease in the blood using images from a smartphone also has been developed. The technology has the potential to solve pressing healthcare problems in developed as well as developing countries, say the researchers.
In an article published in Nature Scientific Reports, titled "Paper and Flexible Substrates as Materials for Biosensing Platforms to Detect Multiple Biotargets," researchers from Florida Atlantic University (FAU; Boca Raton, FL) and their collaborators explain how the integrated cellulose and flexible polyester film technology can address the limitations of current paper and flexible material–based platforms in diagnostic applications.
Using paper and flexible substrates as materials for biosensors, the researchers have identified a rapid and cost-effective way to diagnose diseases and monitor treatment in point-of-care settings. They have been able to show how their new platforms are uniquely able to isolate and detect multiple biotargets selectively, sensitively and repeatedly from diverse biological media using antibodies.