Bioplastic may replace plasticizers in PVC IV tubing


New biobased PHA (polyhydroxyalkanoate) copolymers can replace plasticizers in polyvinyl chloride (PVC), potentially enhancing its acceptability in the medical market.

Metabolix (Cambridge, MA) says it has demonstrated that a series of PHA copolymers miscible with PVC resins improved various physical properties. PHA copolymers, for example, performed as high molecular weight, readily dispersible plasticizers, enabling formulation of compounds with low additive migration and low extractables.

That's a key issue for IV bags and tubing where some major hospital systems, such as Kaiser Permanente, are moving away from PVC because of concerns about plasticizer leaching....

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