An imaging system enclosed in a clear acrylic capsule the size of a large pill has been developed to screen the esophagus for a precancerous condition caused by acid reflux.
"Our main requirements for the capsule material were transparency for near-infrared light and biocompatibility for human use," researcher Michalina Gora tells PlasticsToday. "The material we found working best for us was biomedical grade PMMA."
After it's swallowed, the acrylic capsule is retracted by a flexible tether.
The tool to screen patients for a precancerous condition called Barrett's esophagus, was developed by a team at the Wellman Center for Photomedicine at Massachusetts General Hospital (MGH). Gora is lead author of a report on the technology published in Nature Medicine....